Salivary inflammatory proteins in patients with oral potentially malignant disorders

Oral Cancer and Oral Potentially Malignant Disorders

Prevalence of salivary epstein-barr virus in potentially malignant oral disorders and oral squamous cell carcinoma

BACKGROUND To analyze the presence of salivary Epstein-Barr virus (EBV) DNA in oral squamous cell carcinoma and potentially malignant oral disorders. MATERIAL AND METHODS Three groups were studied: Group 1 (12 oral squamous cell carcinomas (OSCC)), Group 2 (12 potentially malignant oral disorders (PMD)) and Group 3 (47 healthy controls). EBV DNA salivary analysis was performed by PCR. RESUL...

Malignant transformation in 5071 southern Taiwanese patients with potentially malignant oral mucosal disorders

BACKGROUND Oral cancers can be preceded by clinically evident oral potentially malignant disorders (OPMDs). The current study evaluated the rate and the time of malignant transformation in the various OPMDs in a cohort of patients from southern Taiwan. Parameters possibly indicative for malignant transformation of OPMDs, such as epidemiological and etiological factors, and clinical and histopat...

Mast Cell Count Analysis in Oral Inflammatory Lesions, Potentially Malignant Disorders and Oral Squamous Cell Carcinomas

Background: Mast cells have been studied for decades due to their prominent role in normal homeostasis and various pathologies. They display a diversity of roles and are proposed to be a part in the pathogenesis of various pathologic lesions. Aims and Objectives: To histologically evaluate the number of mast cells in tissue sections of oral inflammatory lesions, potentially malignant disorders ...

Oral potentially malignant disorders: Is malignant transformation predictable and preventable?

Leukoplakia is the most common potentially malignant disorder of the oral mucosa. The prevalence is approximately 1% while the annual malignant transformation ranges from 2% to 3%. At present, there are no reliable clinicopathological or molecular predicting factors of malignant transformation that can be used in an individual patient and such event can not truly be prevented. Furthermore, foll...